Clinical Studies
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Evaluating Benefit of a Novel Intra-articular Device in Dogs With a Suspected Cruciate Ligament Tear
Currently EnrollingThis pilot study in dogs with suspected cranial cruciate ligament rupture seeks to determine whether a benefit is seen through the intra-articular injection of a novel veterinary device product in the affected stifle joint.
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Safety and Effectiveness of Long-Acting Intra-Articular and Peri-Neural Injections for the Management of Elbow Pain in Dogs
Currently EnrollingThis is an exploratory study to evaluate the safety and effectiveness of concomitant intraarticular (IA) and peri-neural (PN) injections of an investigational veterinary product for the control of elbow pain in dogs. This 28-day study also includes a long term follow up at 3 and 6 months.
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Evaluating the Tolerability of Combination of Verdinexor and Doxorubicin in Dogs with Cancer
Currently EnrollingVerdinexor is a chemotherapy drug that has been conditionally approved by the FDA for the treatment of canine lymphoma. Verdinexor is a selective inhibitor of nuclear export (SINE) compound, and this family of drug has demonstrated encouraging results in preclinical studies when combined with other chemotherapeutic drugs.
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Long-Acting Analgesic for the Control of Elbow Pain in Dogs
Currently EnrollingThis is an exploratory study to evaluate the safety and effectiveness of concomitant intraarticular (IA) and peri-neural (PN) injections of an investigational veterinary product for the control of elbow pain in dogs. This 28-day study also includes a long term follow up at 3 and 6 months.
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Tolerability of Oral Paclitaxel in Cancer-Bearing Dogs
ClosedResearch Type Ethos Discovery De Novo Study Description Paclitaxel is a human chemotherapeutic that has demonstrated a broad spectrum of activity against several human and canine cancers. Previous formulations of paclitaxel have been poorly absorbed in dogs, limiting its therapeutic value. Oraxol is a novel oral formulation of paclitaxel that is combined with a second
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Canine Lymphoma – Alternating Doxorubicin and TANOVEA®-CA1 for Dogs with Untreated Lymphoma
ClosedThis study may provide information on a multi-drug treatment protocol that may result in improved outcomes for dogs with multicentric lymphoma.
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Ethos Precision Medicine Umbrella Study for Hemangiosarcoma (Ethos-PUSH)
Currently EnrollingEthos Discovery now seeks to deliver a highly advanced clinical trial program investigating the use of novel drugs for the treatment of Hemangiosarcoma (HSA) with the goal of curing this aggressive cancer. This study will ask if drugs specifically matched to the genomic subtypes of patients with HSA will result in improved outcomes.
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Diet to replace Insulin Administration as a Better and Effective Treatment In Clinical (DIABETIC) Cats
Currently EnrollingA new cat diet has been shown to reduce body fat while maintaining lean muscle mass in cats. Accordingly, the following clinical study now seeks to determine if feeding this new diet without concurrent insulin therapy can induce insulin remission in cats with diabetes.
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Diet to complement Insulin Administration as a Better and Effective Treatment In Clinical (DIABETIC) Dogs
ClosedThis clinical study seeks to determine if feeding the new diet in combination with insulin can improve glycemic control in dogs with moderately controlled diabetes.
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Evaluating a New Medication to Control Pain Associated with Osteoarthritis of the Elbow in Dogs
ClosedThe study aims to confirm the effectiveness and safety of a new medicine to control pain associated with osteoarthritis of the elbow in dogs.
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Collection of Biological Specimens from Dogs Scheduled for Biopsy or Surgery for Suspected or Known Cancer
ClosedThis study will compare certain markers in the blood that are specific to cancer, but not found in healthy dogs, before and after surgical biopsy or surgical removal of a mass.
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Collection of Biological Specimens from Dogs Diagnosed with Cancer, but Not Scheduled to Undergo Surgery for Tumor Removal
No Longer EnrollingThis study will compare markers in the blood that are specific to cancer but not found in healthy dogs, before and after treatment for cancer has begun.
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