Clinical Studies
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Probiotic Study in Dogs
OpenWe are studying a novel live probiotic product typically found in the gut of healthy dogs to evaluate the ability of this probiotic to resolve diarrhea in dogs.
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Canine Acute Onset Pancreatitis Study
OpenThis study will evaluate the safety and effectiveness of a newly proposed anti-inflammatory drug in dogs experiencing mild acute onset pancreatitis (AOP) symptoms.
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Evaluation of Liver Protectants for Xylitol Toxicity in Dogs
OpenXylitol is an artificial sweetener commonly found in sugar-free gum. Although safe for humans, xylitol is highly toxic to dogs. This study will compare the liver protective capacity of two veterinary liver protectant products in dogs suffering from xylitol toxicity.
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Oral Melanoma Study in Dogs
OpenThis clinical trial will evaluate the effectiveness of a novel investigational product for the treatment of oral melanoma in dogs.
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Evaluating Benefit of a Novel Intra-articular Device in Dogs With a Suspected Cruciate Ligament Tear
ClosedA new veterinary device composed of collagen and elastin particles has been developed; it is delivered via intra-articular injection and helps protect cartilage from mechanical grinding. This study seeks to validate this device as a pre-surgical management tool for dogs with cruciate disease.
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Safety and Effectiveness of Long-Acting Intra-Articular and Peri-Neural Injections for the Management of Elbow Pain in Dogs
OpenThis is an exploratory study to evaluate the safety and effectiveness of concomitant intraarticular (IA) and peri-neural (PN) injections of an investigational veterinary product for the control of elbow pain in dogs. This 28-day study also includes a long term follow up at 3 and 6 months.
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Evaluating the Tolerability of Combination of Verdinexor and Doxorubicin in Dogs with Cancer
ClosedVerdinexor is a chemotherapy drug that has been conditionally approved by the FDA for the treatment of canine lymphoma. Verdinexor is a selective inhibitor of nuclear export (SINE) compound, and this family of drug has demonstrated encouraging results in preclinical studies when combined with other chemotherapeutic drugs.
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Long-Acting Analgesic for the Control of Elbow Pain in Dogs
OpenThis is an exploratory study to evaluate the safety and effectiveness of concomitant intraarticular (IA) and peri-neural (PN) injections of an investigational veterinary product for the control of elbow pain in dogs. This 28-day study also includes a long term follow up at 3 and 6 months.
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ORBITS Clinical Study
OpenDespite years of active research in the field, high mortality rates associated with sepsis have remained unchanged over the last three decades; we aim to change this!
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Tolerability of Oral Paclitaxel in Cancer-Bearing Dogs
ClosedResearch Type Ethos Discovery De Novo Study Description Paclitaxel is a human chemotherapeutic that has demonstrated a broad spectrum of activity against several human and canine cancers. Previous formulations of paclitaxel have been poorly absorbed in dogs, limiting its therapeutic value. Oraxol is a novel oral formulation of paclitaxel that is combined with a second
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Canine Lymphoma – Alternating Doxorubicin and TANOVEA®-CA1 for Dogs with Untreated Lymphoma
ClosedThis study may provide information on a multi-drug treatment protocol that may result in improved outcomes for dogs with multicentric lymphoma.
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Ethos Precision Medicine Umbrella Study for Hemangiosarcoma (Ethos-PUSH)
OpenIs your dog undergoing surgery for a ruptured splenic tumor? Ethos Discovery would love to have you and your dog participate in our clinical trial! We are evaluating drugs for the treatment of HSA with the goal of curing this aggressive cancer.
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