Clinical Studies

Research Type Ethos Discovery De Novo Study Description Paclitaxel is a human chemotherapeutic that has demonstrated a broad spectrum of activity against  several human and canine cancers. Previous formulations of paclitaxel have been poorly absorbed in dogs, limiting its therapeutic value. Oraxol is a novel oral formulation of paclitaxel that is combined with a second

This study may provide information on a multi-drug treatment protocol that may result in improved outcomes for dogs with multicentric lymphoma.

Ethos Discovery now seeks to deliver a highly advanced clinical trial program investigating the use of novel drugs for the treatment of Hemangiosarcoma (HSA) with the goal of curing this aggressive cancer. This study will ask if drugs specifically matched to the genomic subtypes of patients with HSA will result in improved outcomes.

A new cat diet has been shown to reduce body fat while maintaining lean muscle mass in cats. Accordingly, the following clinical study now seeks to determine if feeding this new diet without concurrent insulin therapy can induce insulin remission in cats with diabetes.

This clinical study seeks to determine if feeding the new diet in combination with insulin can improve glycemic control in dogs with moderately controlled diabetes.

The study aims to confirm the effectiveness and safety of a new medicine to control pain associated with osteoarthritis of the elbow in dogs. 

This study will compare certain markers in the blood that are specific to cancer, but not found in healthy dogs, before and after surgical biopsy or surgical removal of a mass.

This study will compare markers in the blood that are specific to cancer but not found in healthy dogs, before and after treatment for cancer has begun.

The goal of this study is to evaluate changes in procalcitonin levels over time in canine patients surgically treated for sepsis secondary to an abdominal cause (i.e. ruptured intestine). Additional blood sample collection will also be performed to investigate for possible novel markers for sepsis using next generation sequencing for the future development of diagnostic test.

Intestinal dysbiosis has been associated with tumor progression of colorectal, lung, and breast cancer in human patients. To date, no studies have been published investigating the intestinal microbiome in dogs or humans with osteosarcoma (OSA). The objective of this study is to determine whether or not canine patients diagnosed with OSA have intestinal dysbiosis and if the presence of intestinal dysbiosis is associated with metastasis in these patients.

This is study is looking to develop a novel diagnostic test for canine pancreatitis through the identification of genomic markers called exosomes.